Effect art that dominates space

The Art of Scale-Space

Artists pictures rarely have photo-realistic detail. Tools to create pictures from digital photographs might, therefore, include methods for removing detail. These tools such as Gaussian and anisotropic diffusion filters and connected-set morphological filters (sieves) remove detail whilst maintaining scale-space causality, in other words new detail is not created using these operators. Non-pho...

The art of space in the space of art : Edinburgh and its Gallery , 1780 - 1860

In 1792 Edinburgh’s most infamous caricaturist, John Kay, was prosecuted for a satirical portrait which depicted the lawyer, Mr Hamilton Bell in a pedestrian race, carrying a tavern-keeper’s boy in a basket perched on his back.1 Oddly, Kay was prosecuted by the winner of the race, Mr Bell himself, who, like other high and middle-ranking victims of Kay’s pen, took exception to being disclosed in...

Misfolding Dominates Protein Evolution

The diverse array of protein functions depends upon these molecules’ reliable ability to fold into the native structures determined by their amino-acid sequences. Because mutations that alter a protein’s sequence frequently disrupt its folding, protein evolution explores protein sequence space conservatively, either by point mutations or recombination between related sequences. Attempts to engi...

IgE Augments and Dominates

Whole Genome Sequencing demonstrates that Geographic Variation of Escherichia coli O157 Genotypes Dominates Host Association

Genetic variation in an infectious disease pathogen can be driven by ecological niche dissimilarities arising from different host species and different geographical locations. Whole genome sequencing was used to compare E. coli O157 isolates from host reservoirs (cattle and sheep) from Scotland and to compare genetic variation of isolates (human, animal, environmental/food) obtained from Scotla...